| SAR Associates | Ontario |
| Sar Technology, Inc. | British Columbia |
| Saratoga Energy Corporation | |
| Sarbakan | Quebec |
| Sargent Software Solutions | Ontario |
| Sarita Computers | British Columbia |
| Sarnia Lambton Internet & Computer Centre | Ontario |
| Sarvas Design Company | |
| Sasa Kulic | Ontario |
| Sask Interactive | Saskatchewan |
| Saskatchewan Economic Development Alliance | |
| Saskatchewan Indian Institute of Technologies | |
| Saskatchewan Polytechnic | |
| Saskatchewan Research Council | Saskatchewan |
| Saskatchewan Research Network | Saskatchewan |
| Saskatoon Combat Robotics Club | Saskatchewan |
| Saskatoon Linux Group | Saskatchewan |
| Saskatoon TechWorks | |
| SaskEnergy, Inc. | |
| SaskIT | |
| SaskPower | Saskatchewan |
| Sasktchewan Software Services, Inc. | |
| SaskTel | Saskatchewan |
| SaskTel International | Saskatchewan |
| SaskWebs | Saskatchewan |
| SASP Consultants | Ontario |
| Satel Creative | British Columbia |
| Satelcom Internet | Quebec |
| Satellite Marketing | Quebec |
| Satellite Radio Source | Ontario |
| SatelliteWP | |
| Satellos Bioscience | |
| Satisfai Health | |
| SATO Technologies Corporation | |
| SatPhoneCity, Inc. | Alberta |
| Satu Creative Technology | Alberta |
| Saturn Tech Ltd | |
| Saturnsecurity | Quebec |
| Sault College | |
| Sault College - Information Technology Studies | Ontario |
| Sauly Canada | Quebec |
| SauravPro | British Columbia |
| Sauropod Studio | Quebec |
| SAV Technology | British Columbia |
| Savage Data Systems | Ontario |
| Save On Cartridge Plus | British Columbia |
| Save On Laser, Inc. | British Columbia |
| Save The Computer | |
| SaveOnDev | |
| SaveOnHosting | Alberta |