| StationV.com | Manitoba |
| Statslog Software Corporation | Ontario |
| Statup Vancouver | British Columbia |
| Status Marketing | British Columbia |
| Staub Electronics | British Columbia |
| Stax Bill | |
| Stay22 | Quebec |
| Steady Soft, Inc. | |
| Stealth Interactive Media, Inc. | Saskatchewan |
| Stealth Network Services, Inc. | Alberta |
| Steam Design | Quebec |
| Steamclock Software Ltd | |
| Steelman Software Solution, Inc. | Ontario |
| Steeves and Associates | |
| Stega Networks | |
| Steinbach Computer Repair | Manitoba |
| Steintech Computers | Manitoba |
| Stelia Aerospace North America, Inc. | |
| Stella Graphix | |
| Stellar Futures | |
| Stellar Solutions | |
| StellarAlgo | |
| StellarTech Computer Solutions | British Columbia |
| StellarX | |
| Stelvio, Inc. | Quebec |
| Stem Cell Network | |
| Stem Legal Web Enterprises, Inc. | British Columbia |
| STEM Village | |
| StemAxon | Quebec |
| Stemble Leaning, Inc. | |
| STEMCELL Technologies | |
| STEMSOFT Software, Inc. | British Columbia |
| Stenback Web Studios | Ontario |
| Stenberg College | |
| STEP Software, Inc. | Ontario |
| StepForth | British Columbia |
| Stephan Tanguay | Ontario |
| Stéphanie Hétu | Quebec |
| Stepscan Technologies, Inc. | |
| Stereo | Quebec |
| Stéréo Plus | |
| Stereo+ | Quebec |
| Sterling College | |
| Sterling Creations | Ontario |
| Steva Sports Software, Inc. | Ontario |
| Steve Coppin Webs | Ontario |
| Steve Hansen | Ontario |
| Steve simofi | Ontario |
| Steve's Satellite Sales Ltd | Nova Scotia |
| Steven Black Consulting | Ontario |