| Bluestream | British Columbia |
| Bluetrain | Alberta |
| Bluewrist, Inc. | Ontario |
| BluFyre Media | Alberta |
| Bluink Ltd | |
| Blumind | |
| Bluneau Informatique | |
| Bluprint Graphic Design | |
| BluRoot | |
| Bluum Technology | Ontario |
| BluWave, Inc. | Ontario |
| Blyth Academy | |
| BMAK Business and Technology Consultants, Inc. | Ontario |
| BMB Consulting Services, Inc. | Ontario |
| BMC Networks | |
| BmDodo Strategic Design | |
| BMO Apex Startup Challenge | |
| BMPS Software | British Columbia |
| BMU Augmented Intelligence | |
| BMV Optical Technologies, Inc. | Ontario |
| BnCTek | |
| BNF Software | Quebec |
| BNH Expert Software | Quebec |
| BNP Paribas au Canada | |
| Board Checkup | |
| Boardstat | |
| Boast | |
| Bob Gillespie | |
| Bob The Web Page Builder | |
| Bob's Your Uncle | |
| Bobby Bougie | |
| Bochsler Creative Solutions | Ontario |
| Bock Optronics, Inc. | Ontario |
| Bodycote | |
| Boehringer Ingelheim (Canada) Ltd | Ontario |
| Bofu | |
| Bogus Communication | Quebec |
| BOLD | Ontario |
| Bold Commerce | Manitoba |
| Bold Media Group, Inc. | British Columbia |
| Bollé Communications | Quebec |
| Bolster | |
| Bolt Media, Inc. | Ontario |
| Bolt Mobile | Saskatchewan |
| BoltonSmith | Ontario |
| Bombardier | |
| Bombes Créatives | Quebec |
| Bonavista Computer Systems | Alberta |
| Bond Capital | |
| Bond Communications, Inc. | Quebec |