| Fibranet NSP, S.L. | Barcelona |
| Fides Capital | Madrid |
| Fidestamp | |
| Fihoca | Barcelona |
| FileHawk | Barcelona |
| Filmac Centre, S.L. | Valencia |
| Filnet Serveis i Comunicacions, S.L. | Barcelona |
| Fina Biotech | Madrid |
| Financlick | Barcelona |
| Finanzarel | Barcelona |
| Finect | Madrid |
| Finizens | Madrid |
| Finletic Capital SGIC, S.A. | Madrid |
| Finteca | Barcelona |
| Fintech Payments | Madrid |
| Fintonic Servicios Financieros, S.L. | Madrid |
| First Drop VC | |
| Fivecomm | Valencia |
| FiveTech Software, S.L. | Málaga |
| Flame Analytics | Asturias |
| Flanks | Barcelona |
| Flash Park, S.L. | Barcelona |
| Flash Software, S.L. | Zaragoza |
| FlexiDAO SES, S.L. | Barcelona |
| Flipflow | |
| FlipSimply | Madrid |
| Flit2go | Valencia |
| Flomics Biotech, S.L. | Barcelona |
| Florida Centre de Formació | |
| flowww | Valencia |
| FLUZO | Madrid |
| FMIT Solutions | Málaga |
| Fojenet, S.L. | Madrid |
| Fon | Madrid |
| Fontventa, S.L. | Madrid |
| fonYou Telecom, S.L. | Barcelona |
| ForceManager | Barcelona |
| Forged Technologies, S.L. | |
| Formigues.com | Barcelona |
| Foro Digital, S.L. | Murcia |
| Forus | |
| FOSSA Systems, S.L. | Madrid |
| Foundry Iberia | Madrid |
| Four Track Software, S.L | Barcelona |
| FP CEU Madrid | |
| Fracttal Tech, S.L. | Madrid |
| Fractus, S.A. | Barcelona |
| Free Technologies Excom, S.L. | Madrid |
| Freeda Media, S.L. | |
| Freeox Biotech | Barcelona |