| Master Disseny | Barcelona |
| Master N. Automatismos, S.L. | Navarre |
| Mastoner Distribución Informática, S.L.U. | Madrid |
| Masvoz Telecomunicaciones Interactivas, S.L.U. | Barcelona |
| Mata Canaria, S.L. | Las Palmas |
| Matradi, S.L. | Valencia |
| Matrix Development System, S.A. | Barcelona |
| Matrix Electronica, S.L. | Madrid |
| Mawell Net System | Madrid |
| Max Programming, LLC | Alicante |
| MBS Informáticas | Madrid |
| MC Consulting Informático | Murcia |
| MCB Informática | Madrid |
| MCR Info Electronic, S.L. | Madrid |
| Mdtel | Madrid |
| Mecambioamac | Barcelona |
| Mecemsa Consultores, S.A. | Alicante |
| Media Marketing Internet, S.L. | Barcelona |
| Mediaclick conversión, S.L. | Barcelona |
| Mediacloud | Madrid |
| Mediadisseny.com | Barcelona |
| Mediaelx | Alicante |
| Medialabs | Madrid |
| Medicsen | Madrid |
| Mediktor | Barcelona |
| Medios y Redes Online, S.L. | Madrid |
| MediQuo | Barcelona |
| MediterráneaJS | Barcelona |
| Mediterrani University School Barcelona | |
| MedLumics, S.L. | Madrid |
| MedUX | Madrid |
| Meep.app | Madrid |
| Megastar, S.L. | Barcelona |
| Megatró Grup | Girona |
| Mensoft | Madrid |
| Mensoft Consultores, S.L. | Madrid |
| MENTAData Sistemas de Información, S.L. | Madrid |
| Mentioned | Barcelona |
| Mercantil de Informática, S.A. | Madrid |
| Meridiem Games | Madrid |
| Merlin Cantabria | Cantabria |
| Mesala SICI, S.L. | Valencia |
| MESbook | Valencia |
| Mestrelab Research, S.L. | A Coruña |
| Metacampus, S.L. | Barcelona |
| Metacampus, S.L. | Barcelona |
| Metaestudio | Barcelona |
| Metafase | Madrid |
| Metafrase Seguridad Informática | Madrid |
| Metasport Arena, S.L. | Barcelona |