| Zydus Pharmaceuticals, Inc. | New Jersey |
| Zyedge | Virginia |
| Zygo Corporation | Connecticut |
| ZyGo Digital, LLC | California |
| Zygo Industries, Inc. | Oregon |
| Zygon Technologies, Inc. | |
| Zygote Media Group, Inc. | Utah |
| Zykronic, Inc. | Colorado |
| Zylab | Virginia |
| Zylink | California |
| Zylo | Indiana |
| Zylö Therapeutics | |
| ZYMAC, Inc. | New Hampshire |
| ZymagenX, Inc. | California |
| Zymbit | California |
| Zymergi, LLC | California |
| Zymeron | North Carolina |
| Zymo Research Corporation | California |
| ZymoChem | California |
| ZyMōt Fertility, Inc. | |
| ZYMR, Inc. | California |
| Zyne Ventures, LLP | Texas |
| Zynerba Pharmaceuticals, Inc. | |
| Zynergy | Florida |
| Zynex Medical | Colorado |
| Zynga, Inc. | California |
| Zynovo | California |
| Zynx Health, Inc. | California |
| Zypcom, Inc. | California |
| Zype, Inc. | New York |
| Zyphra Technologies, Inc. | |
| Zypsy, Inc. | |
| ZypTV | California |
| ZyraTalk | Arizona |
| Zyston | Texas |
| Zytek Services | Illinois |
| ZyVersa Therapeutics, Inc. | |
| Zyvex Labs, LLC | Texas |
| Zywave | Wisconsin |
| Zywie Bio, LLC | New Jersey |
| ZYYAH | Texas |
| ZZ Biotech, LLC | Texas |
| ZZ Computer | California |
| ZZEE | Delaware |
| [L]earned Media | |
| [s]Cube, Inc. | Massachusetts |
| [x]cube LABS | Texas |
| [x]cubegames | Texas |
| _coderio, LLC | Florida |
| {algo+rhythm} | |