| Xport Communication GmbH | Saxony |
| xpose360 GmbH | |
| XPRENEURS | Bavaria |
| XPS Software GmbH | Bavaria |
| XPS-Finanzsoftware GmbH | Bavaria |
| Xrails Technologies GmbH | Hamburg |
| xsigns GmbH & Co. KG | Lower Saxony |
| xSuite Group GmbH | Schleswig-Holstein |
| XT AG | Bavaria |
| XTablet | Bavaria |
| Xtelligent IT Consulting GmbH | Bavaria |
| xtraport GmbH | Baden-Württemberg |
| XU Group GmbH | |
| Xvid Solutions GmbH | Bavaria |
| XVir Therapeutics GmbH | |
| XY GmbH | |
| Xymatic GmbH | |
| XYplorer | North Rhine-Westphalia |
| Y42 | Berlin |
| Yaak Technologies | |
| Yabado GmbH | Baden-Württemberg |
| Yabeo Capital GmbH | Bavaria |
| YaCy | |
| Yager Development GmbH | Berlin |
| Yalst | Mecklenburg-Vorpommern |
| Yamaichi Electronics Deutschland GmbH | Bavaria |
| YAML for Drupal | Hesse |
| YAML.de | Berlin |
| Yana Framework | Schleswig-Holstein |
| YAPU Solutions GmbH | |
| Yaskawa Europe GmbH | Hesse |
| Yasoon | Baden-Württemberg |
| Yatho | Berlin |
| Yaway Media | Saxony-Anhalt |
| YAY! Digital GmbH | |
| Yeah Can Design Studio UG | Berlin |
| yes!devs GmbH | |
| YGG-Workgroups GbR | Bavaria |
| YIELCO Investments AG | |
| YieldKit UG (haftungsbeschränkt) | Hamburg |
| YND Consult GmbH | Berlin |
| Yolawo GmbH | |
| Yolda GmbH | |
| Yolk – Sebastian Munz & Julia Soergel GbR | Berlin |
| Yonsung GmbH | |
| Yooco GmbH | Bavaria |
| yoocon GmbH | |
| Yook GmbH | |
| YOOtheme GmbH | Hamburg |
| Yopeso GmbH | |