| Name | Region |
|---|---|
| Open | Hauts-de-Seine |
| Open Cascade S.A.S. | Yvelines |
| Open Linking | Nord |
| Open-DSI | Métropole de Lyon |
| Open2be | |
| Openaccess | Paris |
| OpenAgenda | |
| Opencell | |
| OpenClassrooms | Paris |
| OpenCVE | |
| Opendatasoft | |
| Opendev | Puy-de-Dôme |
| OpenFleet | |
| Openhost | Loire-Atlantique |
| OpeningStage | |
| OpenIP | Hauts-de-Seine |
| OpenSpace3D | |
| OpenStudio | Puy-de-Dôme |
| Openteam | |
| OpenXtrem | Charente-Maritime |
| Opera-Fr.com | Paris |
| Ophos.com | Val-de-Marne |
| OPIA Technologies S.A.S. | |
| Opla.ai | |
| OPPIDA | |
| Opquast | Gironde |
| OPSI | Métropole de Lyon |
| Opteam Interactive | Seine-Maritime |
| Optelo | Paris |
| OptiFi | |
| Optify | |
| Optilog | Tarn |
| Optim'BTP | Calvados |
| Optima S.A.S. | Gironde |
| OptimEnergi | |
| Optimiz Construction | |
| Optimmo | |
| Optrium | Hauts-de-Seine |
| Oracle France | Hauts-de-Seine |
| Orakl Oncology S.A.S. | |
| Orange | Paris |
| Orange Business Services | Paris |
| Orange Concept | Paris |
| Orange Cyberdefense | |
| Orange Fab | |
| Orange Lab France | |
| Orange Marine | Paris |
| Orange Store | |
| Orange Ventures | Paris |
| Orasys |