| Defi Web Design | Moselle |
| Degetel | Hauts-de-Seine |
| Degriffmac | Paris |
| Degroof Petercam | |
| Deho Systems | Val-de-Marne |
| DEiiS | Val-d'Oise |
| Delair | |
| Delaware Consulting S.A.S. | |
| DELETEC | Paris |
| Delf | Paris |
| Délibérata | Seine-Maritime |
| DeliCAD | Puy-de-Dôme |
| Delice Robotics | |
| Delight | |
| Deliver.ee | |
| Delixir | Loiret |
| Delpharm | |
| DELSSI | Nord |
| Delta Flash | Bouches-du-Rhône |
| Deltamu | Puy-de-Dôme |
| Deltest S.A.R.L. | Meurthe-et-Moselle |
| Demea Sustainable Investment | |
| DEMLOG S.A.R.L. | Nord |
| Demooz Processing | |
| Demorny Capital | |
| Dendreo | Paris |
| Denis Billo | Var |
| Dental Monitoring | |
| Depaepe | Val-d'Oise |
| Depannaid PC | Loiret |
| Depannpc64 | Pyrénées-Atlantiques |
| Depixus | |
| Derichebourg Aeronautics Training | |
| DESA Logiciels | Yvelines |
| Descartes Underwriting | |
| Design'Partner | Calvados |
| Désirade | Haute-Garonne |
| Desk-Normandie | Calvados |
| DESMAREZ S.A. | |
| Desmo Labs | |
| Dessia Technologies | |
| Dessine ton meuble | |
| Deutsches Historisches Institut Paris | |
| Deux Rien | |
| Dev-id | |
| Devacom | Loire-Atlantique |
| Devanciers | |
| Devconseil | Creuse |
| Devcorp | Paris |
| Devellyn | |