| Project Agora | Attica |
| ProjectWeb | Attica |
| Pronet S.A. | |
| Prosvasi.gr | Attica |
| Protio | |
| Purposeful | |
| Pyrseia Informatics | |
| QIVOS | Attica |
| Qualco | |
| Qualia Pharma | Attica |
| Qualitis S.A. | |
| Quality & Reliability Α.Ε. | Attica |
| Quest | Attica |
| QWise Technologies | |
| R-U | |
| Radio Piraeus Electronics | Attica |
| Rainhost Solutions | Attica |
| rapidbounce | |
| Raycap S.A. | Attica |
| Real Consulting | |
| Reboot bots | Attica |
| Redirect | Attica |
| Regate A.E. | Attica |
| Relational S.A. | Attica |
| Ristart | Central Macedonia |
| Sapce Hellas | |
| Saravanos S.A. | |
| School of Informatics of AUTh | Central Macedonia |
| Science and Technology park of Crete | Crete |
| Scientia Maris | Attica |
| SciFY | |
| SDM | Attica |
| Search Engine Marketing Greece | Attica |
| Sekee | Attica |
| SEO Dominator | Attica |
| Seo Future | Attica |
| Seradis | Attica |
| Shop13 | Attica |
| Sieline A.E. | |
| Sigma Hellas Ltd | |
| Sigmasoft | Central Macedonia |
| Simple Firm, Inc. | Attica |
| SingularLogic | Attica |
| SinisGroup | |
| SKGTech | |
| Skroutz.gr | |
| SLT Samaras | |
| Smart Kit Electronics | Attica |
| Smart NS | Attica |
| Smart Systems A.E. | |