| Syneto | Brescia |
| Synthetic S.r.l. | Messina |
| Syo Solutions S.r.l. | La Spezia |
| SYS-DAT Group | Milan |
| Sys-Tek S.r.l. | Turin |
| Sysaround S.r.l. | Milan |
| SysDesign S.r.l. | Trento |
| Syspack Computer Italia | Rome |
| System Cable S.r.l. | Reggio Emilia |
| System S.r.l. | Livorno |
| System SpA | Modena |
| System-i | Brescia |
| Systematika Distribution S.r.l. | |
| SySTEP S.n.c. | Naples |
| T-LAB | Frosinone |
| T-Lab S.r.l. | Novara |
| T.NET S.p.A. | |
| T4Tech S.r.l. | Genoa |
| Tabasoft | Rome |
| TAC S.r.l. | |
| Tagliabue Sistemi S.r.l. | Milan |
| Taglio C S.r.l. | Cuneo |
| Taitus Software Italia S.r.l. | |
| Takeoff Accelerator | Turin |
| Takis S.r.l. | Rome |
| Talent Garden S.p.A. | |
| Talents Venture | Milan |
| Talete S.r.l. | Milan |
| Tanaza S.p.A. | |
| Target Solutions | Lucca |
| TaTaTu | Rome |
| Tatoosa Creative | Savona |
| Tau Group | Turin |
| Taylora S.r.l. | |
| TD Group Italia S.r.l. | Pisa |
| TE.CO. S.r.l. | Bologna |
| Team Memores Computer S.p.A. | Piacenza |
| TeamDev | Perugia |
| TeamSystem S.p.A. | Pesaro and Urbino |
| Teamwork S.a.s. | Verona |
| Tech2 S.r.l. | Genoa |
| TechChill Milano | |
| Techexperts S.r.l. | Turin |
| TechMass | Milan |
| Techno Center S.p.A. | |
| Technoconference S.r.l. | Florence |
| Technodrive S.r.l. | Milan |
| Technology Nuclear Electronics S.p.A. | Milan |
| Technosind S.r.l. | |
| Technosoft S.a.s. | Genoa |