| Especialistas Web | Mexico City |
| Espora Estudio, S.C. | Mexico City |
| Estrategias Digitales | Mexico City |
| Estratei Sistemas de Informacion | Mexico City |
| Estudio Web | Mexico City |
| Etiennet | Mexico City |
| Eugenia Virtual Humans, S.A. de C.V. | Mexico City |
| Evenplan | |
| Everest Tienda Virtual | Baja California |
| Eversoft | Puebla |
| Evolucione | |
| Evolutiontime | Tamaulipas |
| EVVA Plataforma, S.A.P.I. de C.V. | Mexico City |
| eWorks México | Jalisco |
| Excelencia Consultores en Recursos Humanos, S.A de C.V. | Mexico City |
| Excite | Mexico City |
| Exito Software | Sinaloa |
| Experiencia y Consultoría Integral, S.C. | Mexico City |
| Expert Creations, S.C. | Jalisco |
| Extendo | Mexico City |
| Fábula Comunicación, S.C. | Jalisco |
| Facilito Internet S.A de C.V. | Mexico City |
| Factoro | |
| Facturama | San Luis Potosí |
| Facturama by FreshBooks | |
| Factúrame | |
| Facultad de Estudios Superiores de Cuautla | |
| Facultad Libre de Derecho de Monterrey | |
| Fairplay | Mexico City |
| Fashion Forward MX | |
| Fast Office | |
| FATEC Guaratinguetá | |
| FCDigital Diseño Web | Morelos |
| Felix & Asociados | Sinaloa |
| Feria Mundo Digital | |
| Finamex Casa de Bolsa | |
| Finerio Connect | Mexico City |
| Finnovista | Mexico City |
| Finred Services S.C.P. | Yucatán |
| Fintech on Demand, S.A. de C.V. | |
| Finvero, S.A.P.I de C.V. | Mexico City |
| Flink México | Mexico City |
| Flux QR | Mexico City |
| Foclan | Nuevo León |
| Fondeadora | Mexico City |
| Fortia Technology, S.A. de C.V. | Mexico City |
| FractalCorp | Mexico City |
| Fractalgrafics, S.A. de C.V. | Mexico City |
| FreedomPop México, S.A. de C.V. | |
| Freelan | State of Mexico |