| Nexu | |
| Nexxus Capital | Mexico City |
| NIC México | Mexico City |
| Nordata | Mexico City |
| Northware | Nuevo León |
| Nowports | |
| NRTEC | Mexico City |
| NS DataRecovery | Jalisco |
| nstituto Tecnológico de San Juan del Río | |
| Nubity | |
| Nubloq | Mexico City |
| Nuestro Site de México, S.A. de C.V. | Mexico City |
| Nueve en Red S.A. de C.V. | Mexico City |
| NUFI | |
| Nutrión Software | Jalisco |
| Nuuk | Nuevo León |
| OASA | Mexico City |
| OCapital | |
| Odasoft | Baja California |
| OK Hosting | Mexico City |
| Omanet TI | Durango |
| Omnico de México, S.A. de C.V. | Nuevo León |
| ON Ventures | Mexico City |
| One Card | |
| Orange Studio | Mexico City |
| Orbit Media One | Chihuahua |
| Orcius | Puebla |
| Orion Startups | Mexico City |
| OSRAM México | State of Mexico |
| OT Consulting | Nuevo León |
| Pacto POS | Mexico City |
| Pagaloop | Mexico City |
| Páginas web en Mérida | Mexico City |
| Paginas Web Profesionales | Mexico City |
| Pago Por Clic México | Mexico City |
| Palenca | |
| Palmas | Nuevo León |
| Panngea | Mexico City |
| Parrot Software | |
| Parvada Cowork | Nuevo León |
| Pastor International Marketing, S.A. de C.V. | Quintana Roo |
| Pauta Creativa | Mexico City |
| Payment Power México, S.A. de C.V. | |
| PC Capital | Mexico City |
| PC COM | Mexico City |
| PC Enlaces | San Luis Potosí |
| PC Office | Mexico City |
| Pc Rent | Mexico City |
| PC.com.mx | Mexico City |
| Pcdigital.com.mx | Veracruz |