| CF Consultancy | Utrecht |
| CFM Pharma B.V. | |
| cfunds.io | |
| CG Group | South Holland |
| CGE Risk Management Solutions B.V. | South Holland |
| ChainCraft | |
| ChainPoint B.V. | |
| Channable | Utrecht |
| ChannelEngine | South Holland |
| Channext | Utrecht |
| Chantal Design 92 | Limburg |
| Chargetrip | North Holland |
| Check Technologies B.V. | |
| Chemtrix B.V. | |
| ChipSoft B.V. | North Holland |
| CHL Netherlands B.V. | South Holland |
| Chondropeptix | Limburg |
| Chondropeptix | Limburg |
| Chunk Creative Agency | North Holland |
| CICT Innovations | Utrecht |
| CiMaas | Limburg |
| Cimar Electronics B.V. | Utrecht |
| CimCure | North Holland |
| Cinnamon Interactive | Friesland |
| Cinnovate | Flevoland |
| CipherMail B.V. | North Holland |
| CircleLytics | |
| Circularise | South Holland |
| CirkelAnalyse | Friesland |
| CIS-Websolutions | |
| Cisper Electronics | Flevoland |
| CITC | |
| Cito Benelux B.V. | Gelderland |
| Citryll | North Brabant |
| CKM Extended | Drenthe |
| Claever Systems | Flevoland |
| Clairify B.V. | |
| Claranet Benelux B.V. | North Brabant |
| Classic International B.V. | Limburg |
| Clean Tech Delta | |
| Cleara Biotech B.V. | |
| Cleeng | North Holland |
| Clever Clover | North Holland |
| Cleverware | Gelderland |
| CleVR B.V. | |
| Climate-KIC | North Holland |
| ClimateLaunchpad | |
| CLIQworx | Utrecht |
| Clocktimizer | Utrecht |
| ClockWise | Groningen |