| ProLine | Lower Silesian |
| ProLogistica Soft Sp. z o.o. | |
| Promar | Warmian-Masurian |
| Promarket Computers Sp. z o.o. | Lesser Poland |
| Promatik Sp. z o.o. Sp. k. | Świętokrzyskie |
| Promotech | |
| Propeller.pl Sp. z o.o. | Greater Poland |
| ProperGate Sp. z o.o. | |
| Properis | Lublin |
| ProSAP Sp. z o.o. | Silesian |
| Proscan | Masovian |
| Proster Sp. z o.o. | |
| Proteon Pharmaceuticals S.A. | |
| Protos Venture Capital Sp. z o.o. | Masovian |
| Prowly | |
| Proxi.cloud Sp. z o.o. | Greater Poland |
| Proxmedia | Greater Poland |
| Przedsiębiorstwo Informatyczne CORE | Silesian |
| Przedsiębiorstwo Informatyczne PROKOMP | Świętokrzyskie |
| Przedsiębiorstwo Robót Telekomunikacyjnych S.A. | Pomeranian |
| PS Computer Sp. z o.o. | Lower Silesian |
| PTH Stanpol Sp. z o.o. | Silesian |
| PTR Digital | |
| PU-H SOFTEL Sp. z o.o. | Subcarpathian |
| Pumpa | Lesser Poland |
| Pure Biologics S.A. | |
| PwC Advisory Sp. z o.o. sp.k. | |
| PyramidGames S.A. | |
| Pyrylandia Sp. z o.o. | Masovian |
| Pyszne.pl | |
| PZI Taran Sp. z o.o. | Subcarpathian |
| Q-Glasstech Sp. z o.o. | |
| Q21 | |
| Q4Net Sp. z o.o. | |
| Q7 agencja reklamowa | Kuyavian-Pomeranian |
| QAbird | |
| Qalcwise | Masovian |
| Qarbon IT | |
| QkiZ.pl | Lower Silesian |
| QNA Technology S.A. | |
| Qodeca Sp. z o.o. | Masovian |
| Qodeca Sp. z o.o. | |
| Quantee | |
| Quantum Software S.A. | Lesser Poland |
| Quantum Sp. z o.o. | Lower Silesian |
| Quantumobile | |
| QuatroNET | Lesser Poland |
| QubicGames S.A. | Masovian |
| Quickstream | |
| Quidlo | |