| Premier Web Consultancy | Greater Manchester |
| Premier Website Design Service | Merseyside |
| PremierPrint | |
| Prenostics | |
| PrEP Biopharm | |
| Presbia plc | |
| Prescient Healthcare Group | Greater London |
| Present Pal | |
| Presentation Products Direct Ltd | West Midlands |
| Press Mag Media Ltd | |
| Prestige Designz | Leicestershire |
| Prestige Diagnostics | |
| Presto Web Design | Cambridgeshire |
| Prestwood Software Ltd | West Midlands |
| PretaGov | |
| Prevayl Ltd | |
| Prevention Digital | |
| Previse Ltd | Greater London |
| Prevision Research | |
| Pri-Num Ltd | |
| Priceless Computing | Glasgow |
| PrimaFelicitas | |
| Primal Services | |
| Primal42 | |
| Primary Image Ltd | Essex |
| Primary Networks | Hertfordshire |
| PrimaryBid | Greater London |
| Prime Digital | |
| Prime Ecommerce Solutions | |
| Prime Factor Capital Ltd | |
| Prime Networks | |
| Prime Satcom Consulting Ltd | Bedfordshire |
| Prime Web Solutions Ltd | Surrey |
| PrimePro | |
| Primer API Ltd | |
| Primer Design | |
| Primera Resources | |
| Primesolid | Hertfordshire |
| Primetag | |
| PrimeXeon Ltd | Cambridgeshire |
| Primitive Online | |
| Primo Computers | Surrey |
| Primo Interactive | Cheshire |
| Primo IT | Leicestershire |
| Principal Corporation Ltd | West Sussex |
| Principal Security | |
| Prink Ltd | Staffordshire |
| Print Search Ltd | |
| Printcartridgedirect.com | Flintshire |
| Printed Systems Ltd | Hertfordshire |