| Creativei Media | |
| CreativePixels | |
| CreativeScript Web Design Ltd | |
| Creativesuit | |
| Creativeworld | Lancashire |
| Creativity Sells Ltd | Derbyshire |
| Creatix9 | |
| Creatomatic Ltd | |
| Creator Fund | |
| Credits | |
| Credo Capital Finance Ltd | |
| Credosoft | Edinburgh |
| Creo Consulting Ltd | |
| Creo Medical | |
| Creode | |
| Creotec | Berkshire |
| Crescat Digital Ltd | |
| Crescendo Biologics Ltd | |
| Crescent Consultants Ltd | Leicestershire |
| Crescent Pharma Ltd | |
| Cresconnect | |
| Cresol360 | |
| Crest Software Ltd | Dorset |
| Cretech Ltd | |
| Crewe Colour Printers Ltd | Cheshire |
| Crewe I.T. | |
| Crick Software Ltd | |
| Crimson Solutions Ltd | Greater London |
| Crimson Tide mpro Ltd | Kent |
| Crisp Digital | |
| Crisp Digital Ventures Ltd | |
| Crisp Thinking | |
| Cristie Software Ltd | Gloucestershire |
| Critical Computer Company Ltd | West Sussex |
| Critical Mission Computing Ltd | |
| Critical Power Supplies | Oxfordshire |
| Criton | Edinburgh |
| CRM Cloud | Worcestershire |
| CRM-UK.com Ltd | Oxfordshire |
| crmsquad | |
| CRMT Digital | Berkshire |
| Crocodile Communication Ltd | Glasgow |
| Croft Communications Ltd | |
| Croft Communications Ltd | |
| Croftech Ltd | Greater London |
| Cromwell Business Systems | Cambridgeshire |
| Cron AI | |
| Cronhooks | |
| Crono SaaS Ltd | |
| Cronofy Ltd | |