| Solutions Vet | Quebec |
| Solutions Web & Marketing SLC | Quebec |
| Solutions Web Influence Fx, Inc. | Quebec |
| Solutions Winpunch, Inc. | Quebec |
| Solutions Zen Média | Quebec |
| Solutions360 | Ontario |
| SolutionsIT | Manitoba |
| Solutionwise Consulting, Inc. | Ontario |
| SoluTrek | Quebec |
| Solv-it | |
| Solvera | Saskatchewan |
| Solvira Technology Solutions, Inc. | |
| Solyntek | |
| Soma Media, Inc. | Ontario |
| Someone | Ontario |
| Somm | Ontario |
| Somnia, Inc. | Alberta |
| Somos, Inc. | Ontario |
| Somru Bioscience, Inc. | Prince Edward Island |
| Somun Solutions | Quebec |
| Sona Nanotech | |
| Sonapay | |
| Sonaro, Inc. | |
| Sonder Creative Ltd | Alberta |
| Sonex Computer, Inc. | British Columbia |
| Sonic Interactive Solutions | British Columbia |
| Sonic IT Solutions | |
| Sonic Run | Manitoba |
| Soniccode E-Solutions | |
| SonImage, Inc. | Ontario |
| Sonntag Search Marketing | Saskatchewan |
| SonoCable | British Columbia |
| Sonometrics Corporation | Ontario |
| Sonovision Canada, Inc. | |
| Sonus Microsystems | |
| SONXPLUS | Quebec |
| Sonxplus Val-des-Sources | |
| Sony DADC Canada, Inc. | Ontario |
| Sony of Canada Ltd | Ontario |
| Sophia Software Technologies | |
| Sophos Ltd | |
| Sorger & Co | |
| Soricimed | |
| Soroc | |
| Soroc Technology | Ontario |
| Sortek Electronic Services Ltd | British Columbia |
| SortSpoke | |
| SOS Cartouches | Quebec |
| SOS CIL | Quebec |
| SOS Computer Experts Ltd | British Columbia |