| Orca Health, Inc. | Utah |
| Orca Security | California |
| Orcatec | |
| OrcaWare | California |
| Orchard Digital Marketing | |
| Orchard Operations, Inc. | |
| Orchard Robotics | |
| Orchard Software | Indiana |
| Orchatect | Texas |
| Orchestra BioMed, Inc. | Pennsylvania |
| Orchestra Software | Oregon |
| Orchestrade | California |
| Orchestrate | Ohio |
| Orchestration Services Ltd | |
| Orchid Exchange, Inc. | |
| Orchid Labs, Inc. | California |
| Orchid MPS Holdings, LLC | Michigan |
| Orchun Koroglu | |
| Orcosa, Inc. | New Jersey |
| Ord Digital, Inc. | |
| Ordaos Bio | New York |
| Order.co | |
| Orderadmin | New York |
| OrderCircle | California |
| OrderGroove, Inc. | New York |
| Orderific | |
| Orderly | Georgia |
| Orderly Health | Colorado |
| OrderMyGear, LLC | Texas |
| ORDERS Plus.NET | South Carolina |
| Orders2me | |
| OrderStorm, Inc. | Colorado |
| OrderTech | Arizona |
| Ordex Technology Solutions | |
| Ordinatrix, LLC | Arizona |
| Ordoro | Texas |
| Ordr | California |
| Ordway | District of Columbia |
| Ordway.com | Connecticut |
| Oregon Computer Consultants Association | Oregon |
| Oregon Embedded | Oregon |
| Oregon Entrepreuneurs Network | Oregon |
| Oregon Institute of Science and Medicine | |
| Oregon Institute of Technology | Oregon |
| Oregon Nanoscience and Microtechnologies Institute | |
| Oregon Research Institute | |
| Oregon Social Learning Center | |
| Oregon State Linux Users Group | Oregon |
| Oregon State University Cascades | Oregon |
| Oregon State University Computer Science | Oregon |