| Picis Clinical Solutions, Inc. | Massachusetts |
| Pickaxe | California |
| Pickens Technical College | |
| Pickering Interfaces Ltd | Massachusetts |
| PicketFence.com | South Carolina |
| Pickett & Associates | Indiana |
| PickFu | |
| Pickle Robot Co. | |
| Pickle Robot Company | |
| PickNik, Inc. | Colorado |
| Pickspace | New York |
| Pickteam, LLC | Washington |
| Picktech Innovations | |
| PICMG | Massachusetts |
| Picmonic, Inc. | Arizona |
| Picnic Corporation | |
| PicnicHealth | |
| Pico Digital Marketing | |
| Pico Electronics, Inc. | New York |
| Picocom | |
| picoCTF | |
| Picogrid | |
| Piconics, Inc. | Massachusetts |
| PiControl Solutions | Texas |
| PicoTech Consulting, LLC | Kentucky |
| Picreel | California |
| PICS International | Indiana |
| PICS Telecom International | New York |
| PictoColor Software, Inc. | Minnesota |
| Pictor Labs, Inc. | |
| Pictorus, Inc. | |
| Pictory | Washington |
| Picturesque | Maine |
| Picus Security | California |
| Pidalia, LLC | |
| Pidgeon | |
| Pidgin | Washington |
| piDog Software | Arizona |
| Pie Systems, Inc. | California |
| Pieces for Developers | Ohio |
| Pieces Technologies, Inc. | Texas |
| PieCyfer | |
| Piedmont Technical College | South Carolina |
| Piedmont University | Georgia |
| Piedmont Website Designer | |
| PieMatrix, Inc. | Vermont |
| Pienso | |
| Pieper & Associates | |
| Pierce College District | Washington |
| PierianDx | Missouri |