| Pyramid Business Systems, Inc. | New York |
| Pyramid Communications, SPC | |
| Pyramid Consulting Group, Inc. | Pennsylvania |
| Pyramid Consulting, Inc. | Georgia |
| PYRAMID Laboratories, Inc. | California |
| Pyramid Pharma Services, Inc. | |
| Pyramid Pharma Services, Inc. | |
| Pyramid Semiconductor | California |
| Pyramid Solutions | Michigan |
| Pyrexar Medical | Utah |
| PyroBytes | |
| PyrOjas Corporation | |
| Pyroscope, Inc | California |
| Pyrus | California |
| Pyte | California |
| PyTexas | Texas |
| Pythia | |
| Python 3 Module of the Week | Georgia |
| Python Force Corporation | |
| Python Programming And Numerical Methods: A Guide For Engineers And Scientists | California |
| Python Software Foundation | Virginia |
| pythonGrid | California |
| PyTorch | California |
| Pyx Health | Arizona |
| Pyxel Development | |
| Pyxis Oncology | Massachusetts |
| Pyxl, Inc. | Tennessee |
| Pyxweb, Inc. | |
| Pyze, Inc. | California |
| Q Bio | California |
| Q BioMed, Inc. | New York |
| Q Comp Technologies, Inc. | Wisconsin |
| Q LTD | |
| Q Therapeutics, Inc. | |
| Q'Apel Medical, Inc. | California |
| Q-Biz Solutions, LLC | |
| Q-CAD, Inc. | New Mexico |
| Q-inmass.com | Michigan |
| Q-mation, LLC | |
| Q-Sensei Corporation | |
| Q-Tech Corporation | California |
| Q-Track Corporation | Alabama |
| Q-Vantage | California |
| Q.E.D., Inc. | Massachusetts |
| Q2 Software, Inc. | Texas |
| Q3 technologies, Inc. | Massachusetts |
| Q32 Bio, Inc. | Massachusetts |
| Q4US | |
| Q5 Media | Ohio |
| QA Cafe, LLC | |