| Realvolve | Colorado |
| RealWear, Inc. | Washington |
| RealWebHost | Texas |
| Realync Corporation | |
| Realyze Intelligence | |
| Reardon Web Development | |
| Rearm | |
| ReaSoft Development | Washington |
| Reason One | South Carolina |
| Rebel Ape Marketing | |
| Rebel Base SEO | |
| Rebel Hippo, Inc. | |
| Rebel Holdings, LLC | |
| Rebel Medicine, Inc. | |
| Rebel River Creative, LLC | |
| Rebel Venture Fund | Nevada |
| Rebel Visions Corporation, Inc. | |
| Rebellion Defense, Inc. | |
| RebelMouse | |
| Rebilder, LLC | |
| Rebilly | Texas |
| Rebiotix, Inc. | Minnesota |
| Rebirth Analytics | Washington |
| Reblaze Technologies Ltd | California |
| ReBlood Rx | |
| Rebnord Technologies | Iowa |
| Rebol | California |
| Reboot Imagine | |
| Reboot, Inc. | Illinois |
| Rebound Technologies | Colorado |
| Rebrand Gurus | Wyoming |
| Rebrand Software, LLC | Virginia |
| Rebrandly | California |
| Rebrandly | |
| Rebus Biosystems, Inc. | California |
| REC Philly | |
| Rec Technologies, Inc. | |
| Recapped | New York |
| Recapture | Colorado |
| Recast Software, Inc. | Minnesota |
| Recce | |
| RecCentric | Illinois |
| Recentive Analytics, Inc. | |
| Recepta | Virginia |
| Receptor Life Sciences | Washington |
| Recess | |
| Recess Creative, LLC | |
| Recess, LLC | |
| Recharge | |
| Recharge Capital | |