| Zulip | California |
| Zultech Systems, Inc. | New York |
| Zultys | California |
| Zulu Internet, Inc. | Texas |
| Zūm Rails, Inc. | |
| Zuma | |
| Zuma Technology | California |
| Zuman, Inc. | California |
| Zumasys, Inc. | California |
| Zumeo Design | Oregon |
| Zumigo, Inc. | California |
| Zumper, Inc. | California |
| Zumtek, Inc. | Illinois |
| Zumutor Biologics, Inc. | Massachusetts |
| Zunch, Inc. | Texas |
| Zunify, Inc. | California |
| Zuora | California |
| Zuper | |
| Zuper, Inc. | Washington |
| Zuplo, Inc. | |
| Zupo | |
| Zura Bio Ltd | Nevada |
| Zurb, Inc. | California |
| Zurek Design, LLC | Arizona |
| ZurelSoft, Inc. | California |
| Zurex Pharma | Wisconsin |
| Zurich Medical | Minnesota |
| Zurick Investment Company | |
| ZuriWorks | District of Columbia |
| Zurple | Maryland |
| Zurv, LLC | North Carolina |
| Zuryc, Inc. | North Carolina |
| Zus Health | Massachusetts |
| Zusho Venture Partners, LLC | California |
| ZuSo Dental | Texas |
| Zvelo, Inc. | Colorado |
| Zvetco Biometrics, LLC | Florida |
| ZVOX Audio, LLC | Massachusetts |
| Zwala County Bank | |
| Zweave, Inc. | New Jersey |
| Zwewise, Inc. | Georgia |
| Zwiffer, Inc. | Illinois |
| Zwift, Inc. | |
| ZX Ventures | New York |
| ZXSCRIPT | |
| ZY Therapeutics, Inc. | |
| Zyagen, Inc. | California |
| Zycada Networks, Inc. | California |
| Zycus | New Jersey |
| ZyDoc Corporation | New York |