| Towerstream Corporation | Rhode Island |
| Town Hall Ventures | New York |
| Town.com, Inc. | |
| TownCloud, Inc. | Colorado |
| TownHall Teleconferencing | Virginia |
| Townsend Networks | California |
| Townsquare Interactive | |
| Towson University Department of Computer & Information Sciences | Maryland |
| Towson University Department of Mathematics | Maryland |
| TowXchange, Inc. | Tennessee |
| TOXPLUS | Florida |
| ToxStrategies, LLC | North Carolina |
| Toyon Research Corporation | California |
| Toyota Connected North America | |
| Toyota Research Institute | California |
| Toyota Technological Institute at Chicago | Illinois |
| Toyota Ventures | |
| Toys from my Attic | |
| Tozho | |
| TPC | Washington |
| TPG Direct | |
| TPG Software | Texas |
| TPG Software, Inc. | Texas |
| TPJ Systems, Inc. | Georgia |
| Tplex | |
| TPM, Inc. | South Carolina |
| TPP Web Solutions | Michigan |
| TPS Systems, Inc. | Texas |
| TPSynergy | Texas |
| TPx Communications | California |
| TQA | Texas |
| TQCI Internet Service | Maryland |
| TQI | Ohio |
| TR Computer Sales, LLC | Minnesota |
| Tr1X | California |
| TRA School Software Solutions | North Carolina |
| Traackr | California |
| Trace 3d, Inc. | |
| Trace Applications, Inc. | |
| Trace Biosciences | |
| Trace Neuroscience | |
| Trace Orthopedics | Pennsylvania |
| Trace Space | |
| Trace3, LLC | California |
| Traceable, Inc. | |
| TraceAir Technologies, Inc. | |
| TraceGrains, Inc. | |
| TraceLink, Inc. | Massachusetts |
| Traceloop | |
| Tracer Biotechnologies | |