| Leasecake, Inc. | Florida |
| LeaseHawk | Arizona |
| LeasePilot | Massachusetts |
| LeaseQuery | Georgia |
| Leash Bio | |
| Leather Wallet, LLC | |
| Leave Logic | |
| Leavenworth Online, Inc. | Kansas |
| Lebanon Valley College | Pennsylvania |
| Lebesgue | California |
| LebSEO Design | Florida |
| Lebsontech, LLC | Maryland |
| Lectenz Bio | Georgia |
| Lectron Industries | New Jersey |
| Lectrosonics, Inc. | New Mexico |
| Ledd Studio Design & Development | North Dakota |
| Ledet | Georgia |
| Ledge, Inc. | New York |
| Ledger Run, Inc. | |
| Ledgerwood Associates, Inc. | Arizona |
| Ledgible | Georgia |
| Ledyard Digital Marketing | |
| Ledyard Media | New York |
| Lee College | Texas |
| Lee Digital, LLC | |
| Lee Enterprises | |
| Lee Gustin | Pennsylvania |
| Lee Merkhofer Consulting | Colorado |
| Lee University | Tennessee |
| Leech Lake Tribal College | Minnesota |
| LeedsCode, LLC | Arizona |
| LeeMAH Electronics | California |
| Leena AI, Inc. | California |
| Leenspace | |
| Leepfrog Technologies, Inc. | Iowa |
| Lees-McRae College | North Carolina |
| LeetCode, LLC | |
| LeewayHertz | California |
| Leff Electronics, Inc. | Pennsylvania |
| Left Field Labs | |
| Left Lane Capital | |
| Left Right Mind | California |
| Legacy Capitals, LLC | Pennsylvania |
| Legacy Electronics | South Dakota |
| Legacy Games | California |
| Legacy Search Engine Optimization | Massachusetts |
| Legacy Venture | California |
| Legacy, Inc. | Connecticut |
| Legal Art Works | Florida |
| Legal Files Software, Inc. | Illinois |