| Manifest Technology | Minnesota |
| manifest.ly | Wisconsin |
| Manifesto | |
| Manifold Biotechnologies, Inc. | Massachusetts |
| Manifold, Inc. | |
| Manix Manufacturing, Inc. | Pennsylvania |
| Mankato Web Design | Minnesota |
| Manley Solutions, Inc. | Florida |
| Mann Consulting, LLC | California |
| Manning Publications Co. | New York |
| Mannino Systems | |
| Mannix Marketing, Inc. | New York |
| MannKind Corporation | Connecticut |
| ManoByte | Florida |
| Manolin, Inc. | |
| Manor College | Pennsylvania |
| Manos Accelerator | California |
| Mansell Media | |
| Mansfield + Associates, Inc. | California |
| Mansfield Marketing, LLC | |
| Mansion Ecommerce | Texas |
| Mansoor Technologies | California |
| Manster, Inc. | |
| MANTA | Florida |
| Manta Biosystems, Inc. | |
| Manta Media, Inc. | |
| Manta Technologies, Inc. | Colorado |
| Mantaray Corporation | |
| ManTech International Corporation | Virginia |
| Mantel | Massachusetts |
| Mantera Media | |
| Manticore Games, Inc. | California |
| Mantis Robotics, Inc. | California |
| Mantissa Corporation | Alabama |
| Mantle | |
| Mantra Bio | California |
| Mantra IT Solutions, LLC | |
| Mantra Technologies | |
| Manty Web Designs | Texas |
| Manufactur | |
| Manufacturers Components, Inc. | Florida |
| Manufacturing 360 Consulting | Pennsylvania |
| Manufacturing Action Group, Inc. | Michigan |
| Manufacturing Business Technology | |
| Manufacturing Information Solutions | Indiana |
| Manufacturing Information Systems, Inc. | Vermont |
| Manufacturing Works | Wyoming |
| Manus Bio, Inc. | |
| Manutara Ventures | Florida |
| Manutech, Inc. | Florida |