| University of Sussex - Department of Mathematics | East Sussex |
| University of Sussex - School of Engineering and Informatics | East Sussex |
| University of Sussex - Sussex Centre for Quantum Technologies | East Sussex |
| University of the Arts London | |
| University of the Highlands and Islands | |
| University of the West England Bristol - School of Computing and Creative Technologies | Bristol |
| University of the West of England Bristol | Bristol |
| University of the West of Scotland | |
| University of Wales | Cardiff |
| University of Wales Trinity Saint David | Carmarthenshire |
| University of Wales Trinity Saint David - Computing | Swansea |
| University of Warwick | West Midlands |
| University of Warwick - Department of Computer Science | West Midlands |
| University of Warwick Computing Society | Warwickshire |
| University of Warwick Mathematics Institute | West Midlands |
| University of Warwick Science Park | West Midlands |
| University of West London | Greater London |
| University of Westminster | Greater London |
| University of Westminster - Centre for Parallel Computing | Greater London |
| University of Winchester | |
| University of Wolverhampton | West Midlands |
| University of Wolverhampton - School of Engineering, Computing and Mathematical Sciences | West Midlands |
| University of Worcester | |
| University of York | North Yorkshire |
| University of York - AudioLab | |
| University of York - Department of Mathematics | North Yorkshire |
| Uniware Systems Ltd | |
| Uniwell EPOS Systems | West Yorkshire |
| UNL Solutions Ltd | Leicestershire |
| Unlimited Coders Ltd | |
| Unlimited Web Hosting UK Ltd | Greater Manchester |
| Unmade Ltd | |
| Unmind Ltd | |
| Unrest World Ltd | |
| Unrival Ltd | |
| UNRVLD Ltd | |
| Unspun Digital | |
| Unstructured Media | |
| Unstuck Design Ltd | Wiltshire |
| Untangled Web | Scottish Borders |
| Untangled.Finance | |
| Unyted Ltd | |
| UP Hotel Agency | |
| Up Learn Ltd | |
| UP Ventures Group | |
| UpFront Diagnostics | |
| Upgrade Education | |
| Upgrade Options Ltd | Surrey |
| Uphold Europe Ltd | |
| Upkeep Training | |