| Dean Loh | Singapore |
| Decacorn Capital | Singapore |
| Decentro | Singapore |
| DeCrew I/O | Singapore |
| Dedoco Pte Ltd | Singapore |
| Deep Fried Brain | Singapore |
| Deep Identity | Singapore |
| DeepMoo | |
| Defence Science and Technology Agency | Singapore |
| DeFiance Capital | Singapore |
| DEHA Global | |
| Delta Spike Pte Ltd | |
| DeMellows | Singapore |
| Denron Computers & Networks | Singapore |
| Design Prodigy Pte Ltd | Singapore |
| Design Sojourn | Singapore |
| Design Start | |
| Designs.ai | Singapore |
| Devknox | |
| DEX Ventures Pte Ltd | Singapore |
| DFG | Singapore |
| Difilm | Singapore |
| Digi Brand | |
| Digibrand | |
| Digiland Pte Ltd | Singapore |
| DigiMar Con Southeast Asia | |
| DigiPen Institute of Technology Singapore | Singapore |
| Digital 38 | |
| Digital Alpha Marketing Pte Ltd | Singapore |
| Digital Edge (Singapore) Holdings Pte Ltd | |
| DiGiTaL Information Systems Pte Ltd | Singapore |
| Digital Insights Ventures | Singapore |
| Digital Marketing Agency Singapore | |
| Digital Media Partners Pte Ltd | Singapore |
| Digital Network Access Communications | Singapore |
| Digital Squad | |
| Digital-Media-Lab | Singapore |
| Digitall Creations Pte Ltd | Singapore |
| Digitro Pte Ltd | Singapore |
| DigitwinSG | |
| Dimension Data | Singapore |
| DIMENSIONS International College | |
| Disruptive Digital | Singapore |
| Distributed Energy Pte Ltd | Singapore |
| Distributed Ledger Technologies Pte Ltd | Singapore |
| DISTRII Singapore | Singapore |
| DocDoc Pte Ltd | |
| Docquity | Singapore |
| Doctor Anywhere | Singapore |
| Dolgix | Singapore |