| SOS electronic, s.r.o. | Košice |
| Source-Code | |
| Speekle, s.r.o. | |
| Spinbotics | |
| SQP International, s.r.o. | Banská Bystrica |
| Staffino s.r.o. | Bratislava |
| Stanislav Klubert | Košice |
| Starbug, s.r.o. | Žilina |
| Startitup.sk | |
| Startup centrum | |
| STEP software, s.r.o. | Košice |
| Sting-Energo, s.r.o. | |
| Stix, s.r.o. | Žilina |
| Storm, s.r.o. | |
| Stormware, s.r.o. | Bratislava |
| Studio Style | Bratislava |
| Styleweb | Bratislava |
| SunSoft | Žilina |
| superfaktura.sk, s.r.o. | Bratislava |
| Supermobilioty.SK | Trenčín |
| SuperScale | |
| SVOP, spol. s r.o. | Bratislava |
| SWAN, a.s. | Bratislava |
| Sygic | Bratislava |
| Synapsys, s.r.o. | Bratislava |
| Synetics | Trenčín |
| Syntegra Systems | Bratislava |
| SysCom | Bratislava |
| SYSKOS, s.r.o. | |
| Sysoon, s.r.o. | |
| Systematic, s.r.o. | |
| Systemios Ltd | |
| SZM.com | Bratislava |
| T-MAPY Slovensko, s.r.o. | Banská Bystrica |
| TABI Corp., s.r.o. | Trnava |
| Tangram SW, s.r.o. | Prešov |
| Tarantula, s.r.o. | Bratislava |
| Tatra banka, a.s. | Bratislava |
| TCNS, s.r.o. | Bratislava |
| TCP - Technology MAS, s.r.o. | |
| Team-SOFT, s.r.o. | |
| TECHBOX, s.r.o. | Bratislava |
| Technická Univerzita v Košiciach | Košice |
| Technická univerzita vo Zvolene | Banská Bystrica |
| Technoplus, spol. s r.o. | |
| TECHSOFT, s.r.o. | Prešov |
| TechStore.sk | Prešov |
| Tecton a.s. | Bratislava |
| TED Notepad | Bratislava |
| TEKRA.sk | Trnava |