| Quantis Informatik AG | Zug |
| Quantonomics GmbH | |
| Quantum Resistant Ledger Foundation | |
| Quercis Pharma AG | |
| Quickline AG | Bern |
| Qumea AG | |
| Quotient Suisse S.A. | |
| R-Elektronik AG | St. Gallen |
| Racefish AG | |
| Radicle | |
| Raidix International | Nidwalden |
| Rainfall | Zug |
| RaiseNow AG | |
| Raized.ai AG | |
| RAK Software-Entwicklung | Thurgau |
| RALE Engineering GmbH | Aargau |
| Raptus AG | Bern |
| Rase IT-Services GmbH | Lucerne |
| Raskin Software, LLC | Zurich |
| Raumpioniere.ch | St. Gallen |
| Raw Labs S.A. | |
| RC2 Electronique S.A. | Vaud |
| RDS.ch | Aargau |
| Real Fake | |
| Realiscape | |
| Realtime Soft AG | Bern |
| RealTyme S.A. | |
| Recom Electronic AG | Schwyz |
| Redalpine Venture Partners AG | Zurich |
| Redbiotec AG | |
| Reference Capital | |
| Référencement Suisse | Geneva |
| REFUSiON Ltd | Zurich |
| Regen Lab S.A. | |
| Reichle & De-Massari AG | Zurich |
| Rejuveron Life Sciences AG | |
| Relai | Zurich |
| Relec | Vaud |
| Relief Therapeutics Holding S.A. | |
| Relio AG | |
| Relmatic AG | Zurich |
| Remedok | |
| Renata S.A. | Basel-Landschaft |
| René Faigle AG | Zurich |
| REO Elektronik AG | Zurich |
| ReSe Applications GmbH | St. Gallen |
| Resolve S.A. | |
| responsAbility Investments AG | |
| retailsolutions Schweiz AG | Zug |
| Retel Neuhausen AG | Schaffhausen |