| Rehabtronics, Inc. | |
| Rehash Digital | |
| RehvUp Technologies, Inc. | |
| Reimer Digital | |
| Reis Informatica | |
| Reko International Group, Inc. | Ontario |
| REL Software | British Columbia |
| Relasoft Solutions, Inc. | Ontario |
| Relate | |
| Relation1 | Quebec |
| Relay Platform | |
| Relay Ventures | |
| Release Dynamics | British Columbia |
| Relentless Technology | British Columbia |
| Relevant Connections, Inc. | |
| Reliable Customized Solutions Ltd | British Columbia |
| Reliable Security Solutions, Inc. | Ontario |
| Reliant Technologies Solutions Group | |
| Reliantech | |
| Relic Entertainment | British Columbia |
| Relish Studios | Ontario |
| Relocom Enterprises | Ontario |
| RelyOn | Ontario |
| REM Web Solutions | Ontario |
| remitAnywhere | Ontario |
| Remitbee, Inc. | |
| Remote Possibilities | |
| RemoteTek International Services | Ontario |
| Remsoft | New Brunswick |
| Renaissance Computer Solutions, Inc. | Ontario |
| Renaissoft | British Columbia |
| Renaps | Quebec |
| Rendu Design | Quebec |
| René St-Pierre | Quebec |
| Renesis | |
| Renewal Funds | British Columbia |
| Renewd Computer Technology | Ontario |
| Renewed Technology Ltd | Saskatchewan |
| Renewity Systems, Inc. | Ontario |
| Renix, Inc. | |
| Renovaweb | Quebec |
| Renoworks | Alberta |
| Rent Centric, Inc. | Ontario |
| Rent Relay | Ontario |
| Rent-A-Nerd Computer Services, Inc. | British Columbia |
| RentalPoint Software | Ontario |
| Rentrax | |
| Rentsync | |
| Reonix Automation, Inc. | |
| Repair Labs | Ontario |