| SGS Compuwave | Ontario |
| SGS Geological Services | Quebec |
| SGX Informatique | Quebec |
| SH1FT | Quebec |
| Shabodi | |
| Shad Canada | |
| Shade.ca | Quebec |
| Shadow Software and Consulting, Inc. | |
| Shadowbox Learning Services, Inc. | Ontario |
| Shadowline POS Systems, Inc. | |
| ShadowSoft Solutions | |
| Shakepay | |
| Shalkin Consulting | |
| Shamans.ca | Ontario |
| Shamrock Designs | |
| SHAN Solutions | Ontario |
| Shane's Computer Service | Ontario |
| Shanked Computer Recycling, Inc. | Alberta |
| Shapesoft | |
| Sharbot.com, Inc. | Ontario |
| Share IT North America, Inc. | Ontario |
| ShareArchiver | Ontario |
| Shared Reality Lab | Quebec |
| ShareGate | |
| Sharesmart | |
| Sharethrough | |
| ShareVision | |
| Shark Media & Sport | Quebec |
| Sharkbyte, Inc. | |
| Sharp Electonics of Canada Ltd | Ontario |
| Sharp Immersive | |
| Sharp Innovation Solutions, Inc. | Ontario |
| Sharp Point Data Ltd | Ontario |
| Sharpeshooter Computer Services | Alberta |
| Shastaind.com | Manitoba |
| Shaw Broadcast Services | Ontario |
| Shaw Communications | Alberta |
| Shaw Computer Systems, Inc. | Ontario |
| Shawinigan Informatique | Quebec |
| Shawn Bisaillon | Quebec |
| Shawn Duggan | Nova Scotia |
| Shawn Johnston | British Columbia |
| SHEA Business Solutions Ltd | Ontario |
| Shearwater Aerospace, Inc. | |
| Sheena Studios | British Columbia |
| Shelburne Computer Centre | Ontario |
| Shelley Automation | Ontario |
| ShelTek Holdings | |
| Shep Ltd | |
| Sherbrooke Innopole | |