| Xactly Design & Advertising | Ontario |
| Xahive, Inc. | Ontario |
| Xanadu | Ontario |
| Xanantec Technologies, Inc. | Alberta |
| Xanatos Marine Ltd | British Columbia |
| XAP Corporation | British Columbia |
| XapCard, Inc. | Ontario |
| Xavier Frenette | Quebec |
| XBASE Technologies Corporation | Ontario |
| Xcare | |
| XCCommerce | Quebec |
| Xceed, Inc. | Quebec |
| Xcel Source Corporation | Ontario |
| Xcellence Automatisation, Inc. | Quebec |
| XCG Consulting Ltd | |
| Xcyte Digital Corporation | Ontario |
| XdigitalNet | British Columbia |
| XDL | Ontario |
| XE.com, Inc. | |
| Xediton Pharmaceuticals, Inc. | Ontario |
| Xelaration Software | Quebec |
| Xelerance Corporation | Ontario |
| Xello, Inc. | |
| Xello, Inc. | |
| Xelys | Quebec |
| Xenex Enterprises, Inc. | Ontario |
| Xenium IT Corporation | |
| Xeno Games | Quebec |
| Xenon Pharmaceuticals, Inc. | |
| Xenoom Technologies | Quebec |
| Xentrax | Ontario |
| Xeo Marketing & Strategic Consultancy, Inc. | Ontario |
| Xeos Technologies, Inc. | Nova Scotia |
| Xerox Canada | Ontario |
| XGen Studios, Inc. | Alberta |
| XGestion, Inc. | Quebec |
| Xguru | Ontario |
| XI Digital | Ontario |
| xiBOSS Corporation | Ontario |
| XiiTec IT Solutions, Inc. | British Columbia |
| Xilligence | Ontario |
| Xiphos Systems Corporation | Quebec |
| Xittel | Quebec |
| XLPub, Inc. | Quebec |
| XLSCOUT | |
| xMac informatique et communications, Inc. | Quebec |
| XMachina | |
| XMedius | Quebec |
| XMetaL | British Columbia |
| XMG Studio, Inc. | Ontario |