| Xn Québec | Quebec |
| Xod Media | Ontario |
| Xogenus | Ontario |
| XOPHOS Conseils Canada | Quebec |
| Xorlogics | British Columbia |
| Xorosoft | British Columbia |
| XORTX Therapeutics, Inc. | |
| Xpan | Alberta |
| Xpan, Inc. | |
| XPC Web Hosting | British Columbia |
| Xperigo | |
| Xperio Labs Ltd | |
| Xpert-Micro | Quebec |
| Xpertics solutions, Inc. | Quebec |
| Xpertkeyboard | British Columbia |
| Xpira Pharmaceuticals | |
| Xplor Canada Association | Ontario |
| Xplornet Communications, Inc. | New Brunswick |
| XPMsoftware, Inc. | Ontario |
| xPosito | Quebec |
| Xpress Center Acessories Ltd | British Columbia |
| XpressTec Corporation | Ontario |
| XPS Group | |
| XPV Water Partners | Ontario |
| Xquisit Communications | Ontario |
| XR Immersive Tech, Inc. | |
| xSELLence | |
| Xsite | Ontario |
| xsitra | Alberta |
| XST Xpert Solutions Technologiques | Quebec |
| XStandard | Ontario |
| xStudio.ca | Ontario |
| Xtech Solutions, Inc. | Alberta |
| Xtel International Ltd | Alberta |
| XTLabs, Inc. | Alberta |
| Xtra PC, Inc. | New Brunswick |
| Xtract One Technologies | Ontario |
| Xtrem Informatique | Quebec |
| XTREME Creative Media Solution | Ontario |
| Xtron Imaging, Inc. | Ontario |
| Xtube Multimédia | Quebec |
| Xuzo.com | British Columbia |
| Xyfon Solutions, Inc. | British Columbia |
| Xylotek Solutions, Inc. | Ontario |
| Xyntax Group, Inc. | Alberta |
| Xyris Illustrative Design | British Columbia |
| XYTERA Electronics | Quebec |
| X_times_Y, Inc. | British Columbia |
| Y C Systems | Ontario |
| Y M & Company | Ontario |