| Our Internet | Florida |
| Our Layd of the Lake University | Texas |
| OurBizSpace | New York |
| OurGig.com | California |
| Ouro Medicines | |
| OurRecords, Inc. | |
| Ours Global | Wyoming |
| OurWebmaster | Oregon |
| Ouster, Inc. | California |
| Out of a Jam Solutions | Alaska |
| Out of Bounds Communications, LLC | Missouri |
| Out Of Nowhere | Texas |
| Out of the Box Marketing | Oregon |
| Out There Web Designs, LLC | |
| OutagesIO | Arizona |
| Outback Solutions | California |
| Outbound AI | Washington |
| OutboundEngine | Texas |
| Outbounds Auto Transport | |
| Outbrain, Inc. | New York |
| Outburst Web, LLC | Indiana |
| Outcomes | Florida |
| Outcomes Research Consortium | |
| Outcomes4Me, Inc. | |
| Outcrowd, Inc. | |
| OUTDO, Inc. | |
| Outdoorsy, Inc. | |
| Outer Biosciences | |
| Outerbase | |
| OuterBox, Inc. | Ohio |
| Outerlink Corporation | Massachusetts |
| Outfield | Texas |
| Outfitter Satellite, Inc. | Tennessee |
| Outformations, Inc. | California |
| Outgo, Inc. | Washington |
| Outgrow | |
| Outillage Avitec, Inc. | |
| Outlander VC | New York |
| Outliant | |
| Outlier AI, Inc. | California |
| Outlier Solutions, Inc. | |
| Outlier Technologies, Inc. | Ohio |
| Outlook Technology, Inc. | Florida |
| Outlook Therapeutics, Inc. | |
| Outloud | California |
| OutofToner.com | Arizona |
| Outpace Bio | Washington |
| Outpace SEO | Oklahoma |
| Outpatient Imaging Affiliates, LLC | Tennessee |
| Outplay | Texas |