| Lac Courte Oreilles Ojibwe University | Wisconsin |
| LAC Portland | Oregon |
| Lacamas Laboratories, Inc. | |
| LACED Agency | |
| Lacework, Inc. | California |
| Lachman Consultants | |
| LaCie | California |
| Lackawanna College | Pennsylvania |
| Lackawaxen Telecommunications Services | Pennsylvania |
| Laconia Capital | New York |
| LaCroix Optical Co. | Arkansas |
| Lactiga | |
| Lactiga US, Inc. | |
| LACUNA Digital | |
| Lacuna Strategies, LLC | |
| LAD Solutions | California |
| Ladder Bio, Inc. | |
| Ladder Technologies, Inc. | |
| Ladders, Inc. | |
| Lade, LLC | |
| Ladezign, LLC | |
| LadRx Corporation | California |
| LADS Network Solutions, Inc. | Missouri |
| Laducer & Associates, Inc. | North Dakota |
| Ladue, LLC | North Carolina |
| Lady Web Pro | Idaho |
| LadyBird InfoTech | Texas |
| Ladybugz Interactive Agency | Massachusetts |
| Lafayette College | Pennsylvania |
| Lafayette College Computer Science | Pennsylvania |
| Lagniappe Media | Louisiana |
| Lagoon Information Systems, Inc. | California |
| LaGrange College | Georgia |
| Lagrange Labs, Inc. | |
| Laguna Biotherapeutics, Inc. | |
| Laguna Tech | |
| LahakX | California |
| Lahey Computer Systems, Inc. | Nevada |
| Laiba Technologies, LLC | Wyoming |
| Laicos, Inc. | Nevada |
| Laiken Consulting | |
| Lair East Labs | New York |
| LairWare Ltd | New Mexico |
| Laisha Designs | Maine |
| Lake Area Technical College | South Dakota |
| Lake County Computers, Inc. | |
| Lake Erie College | Ohio |
| Lake Forest College Computer Science | Illinois |
| Lake Forest College Mathematics | Illinois |
| Lake Land College | Illinois |