| Laxir | California |
| Laxis, Inc. | California |
| Laxxon Medical | New York |
| Layer 7 Innovations, Inc. | |
| Layer AI, Inc. | |
| Layer Financial Technologies, Inc. | |
| Layer Health | |
| Layer One Cabling, Inc. | Florida |
| Layer One Media, Inc. | Wisconsin |
| Layer One Networks, LLC | |
| Layer Project, Inc. | |
| Layer5, Inc. | Texas |
| Layer8 Consulting, Inc. | Maryland |
| LayerBio | Massachusetts |
| Layered Solutions, Inc. | |
| Layered Systems, LLC | Wisconsin |
| LayerOne | California |
| LayerZero Power Systems, Inc. | |
| Layman's PC Sales and Service | West Virginia |
| Layton Technology | Florida |
| Laza Medical, Inc. | |
| Lazar Consultants, LLC | New Jersey |
| Lazard | |
| Lazarev | |
| Lazarus Data Recovery | California |
| Lazarus New York City | |
| Lazesoft | Minnesota |
| Lazurite | Ohio |
| Lazworld.com, Inc. | New Jersey |
| LazyProgrammer.me | New York |
| LazyVim, Inc. | |
| LB Pharmaceuticals, Inc. | |
| LBA Group, Inc. | North Carolina |
| LBI Software | New York |
| LBiSat, LLC | |
| LBM Systems, LLC | Connecticut |
| LBMC Tech | Tennessee |
| LBRY, Inc. | |
| LC Networks, Inc. | California |
| LC Sciences | Texas |
| LC Technologies, Inc. | Virginia |
| LC Wiring | California |
| LCDPanels | Texas |
| LCF Enterprises | Idaho |
| LCG Consulting | California |
| LCL Electronics, Inc. | Minnesota |
| LCS | Ohio |
| LCX Software, Inc. | New Hampshire |
| LDAPSoft Corporation | Illinois |
| LDR Ventures | California |