| Sozialhelden e.V. | |
| SP Data GmbH & Co. KG | North Rhine-Westphalia |
| SP Vertriebs GmbH | Baden-Württemberg |
| SP-Software GmbH | Lower Saxony |
| Space Founders | |
| Space IC GmbH | |
| Space Squad | |
| Space Structures GmbH | |
| Space Tech Expo Europe | |
| Space Ventures GmbH | |
| Space2000 | Mecklenburg-Vorpommern |
| Spacebase GmbH | |
| SpaceCAD | Baden-Württemberg |
| spacedealer GmbH | |
| Spacegoats GmbH | |
| SpaceIndex UG (haftungsbeschränkt) | Mecklenburg-Vorpommern |
| SpaceNet AG | Bavaria |
| Spaceopal GmbH | |
| spacepilots GmbH | |
| Spaceteams GmbH | |
| SpaceTec Capital GmbH | |
| SpaceTech GmbH | |
| SpaceWatch.Global GmbH | |
| spaceXmedia | Saarland |
| Spaciv | |
| Spamihilator | Hesse |
| Sparetech GmbH | |
| Spark Networks SE | Berlin |
| Sparkm4n Webdesign | |
| Sparkybit | |
| Sparrow Analytics GmbH | |
| Spath Printware + Service GmbH & Co. KG | |
| Spatz.Digital | Saxony-Anhalt |
| SPAUN Electronic GmbH & Co. KG | Baden-Württemberg |
| SPB Systemorientierte Planungs- und Beratungsgesellschaft mbH | Bremen |
| SPE Systemhaus GmbH | |
| Speakeasy Berlin GmbH | |
| Specter Automation GmbH | |
| Spectra GmbH & Co. KG | Baden-Württemberg |
| Spectra PC & Peripherie GmbH | Baden-Württemberg |
| Spectral Service AG | |
| Spectrm Publishing UG | |
| Spectrum Systementwicklung Microelectronic GmbH | Schleswig-Holstein |
| SPEED Elektronik Vertrieb GmbH | North Rhine-Westphalia |
| Speed Kit | |
| Speed4Trade GmbH | Bavaria |
| Speedlink GmbH | Lower Saxony |
| SpeedPartner GmbH | |
| Speexx | |
| Spegg Kopier- und Informationssysteme GmbH | Hesse |