| Symanto | Bavaria |
| SYMAX Business Software AG | Hesse |
| Symbiolab GmbH | |
| Symbiosys2 | |
| SymbioWare IT GmbH | Bavaria |
| Symferon GmbH | Hesse |
| Symmedia GmbH | North Rhine-Westphalia |
| Symmetrix Design & Hosting | Hesse |
| sympacon Beratungsgesellschaft mbH | Lower Saxony |
| Sympatient GmbH | |
| SYMPLASSON Informationstechnik GmbH | Hamburg |
| SymProject GmbH | |
| Symweb GmbH | Baden-Württemberg |
| synalis GmbH & Co. KG | North Rhine-Westphalia |
| Synapse Audio Software | Baden-Württemberg |
| Synapsy Mobile Networks GmbH | Bavaria |
| Synaptic Network GmbH | Bavaria |
| Synaptic Systems GmbH | |
| Synapticon GmbH | |
| Synaxon AG | North Rhine-Westphalia |
| SynchPST | Bavaria |
| Syncope Communication Systems GmbH | Hamburg |
| Synctive GmbH | |
| SyncTwin GmbH | |
| Syncwork AG | Saxony |
| Syndicat IT & Internet | Lower Saxony |
| Syndicats eG | |
| Syneco Trading GmbH | |
| Synera GmbH | |
| Synerpy GmbH | Bavaria |
| Synertronixx GmbH | Lower Saxony |
| Synetics Gesellschaft GmbH | North Rhine-Westphalia |
| Synimmune GmbH | |
| Synium Software GmbH | Rhineland-Palatinate |
| SYNLAB International GmbH | |
| Synovo GmbH | |
| Synsor.ai GmbH i.L. | |
| SynSpace Group GmbH | Baden-Württemberg |
| Syntactix | Hesse |
| SyntaX Software | Hesse |
| SyntaxPhoenix | |
| syntesion GmbH | |
| syntevo GmbH | Bavaria |
| Synthflow AI | |
| Syntlogo GmbH | Baden-Württemberg |
| Synx GmbH & Co. KG | Baden-Württemberg |
| Syracom AG | Hesse |
| Syrakus Holding AG | |
| SYS TEC electronic GmbH | Saxony |
| Sys-Manage | Hesse |