| Rachip | Tel Aviv District |
| RAD | Tel Aviv District |
| RAD BioMed Accelerator | Tel Aviv District |
| RADA Electronic Industries Ltd | Central District |
| Radcom Ltd | Tel Aviv District |
| Raddion Ltd | Tel Aviv District |
| Radiflow | |
| Radiflow Ltd | Tel Aviv District |
| Radix Technologies Ltd | Tel Aviv District |
| Radview Software | Central District |
| Radware | Tel Aviv District |
| RADWIN Ltd | |
| Rafa | |
| Rafael Advanced Defense Systems Ltd | |
| Rafael Development Corporation Ltd | Tel Aviv District |
| Raftt | |
| Raicol Crystals | |
| RAID Recovery Online | Tel Aviv District |
| Rakuto Kasei (Israel) Ltd | |
| Rambam Health Care Campus | |
| Ramot - Technology Transfer Company of Tel Aviv University | |
| Random Forest VC | Tel Aviv District |
| RangerMSP | |
| Rapac Communication & Infrastructure Ltd | Central District |
| Rapid Medical | Northern District |
| Rappaport Institute | Haifa District |
| Rashim Information Systems Ltd | Tel Aviv District |
| RavenDB | |
| RavTech | Tel Aviv District |
| RAZ Information Systems Ltd | Tel Aviv District |
| Razi Interactive | Tel Aviv District |
| RazzTech | Northern District |
| Re:Tech | Tel Aviv District |
| ReactNext | Tel Aviv District |
| Really Good Code Ltd | Tel Aviv District |
| Reconcept SEO Ltd | Tel Aviv District |
| Record | Tel Aviv District |
| Red Access | Tel Aviv District |
| Red Bird | |
| Red Dot Capital Partners | Tel Aviv District |
| Redefine | Central District |
| RedHill Biopharma Ltd | |
| Redmatch | Central District |
| Redtree Solutions | Tel Aviv District |
| REE | Tel Aviv District |
| Reflectiz | |
| RegenoGel | |
| Regentis Biomaterials | |
| Regulus | Haifa District |
| Rehost Ltd | Tel Aviv District |