| Ryan Manufacturing, Inc. | British Columbia |
| Ryan Thomson | British Columbia |
| RYCOM, Inc. | Ontario |
| Rycor | |
| Rycor | |
| Ryerson University | Ontario |
| Ryerson University - Department of Electrical and Computer Engineering | Ontario |
| Rynd Biotech | |
| Ryse Creative Consultancy | Ontario |
| Rytalo | Ontario |
| Rytech Computer Solutions | Ontario |
| Ryzn Enterprise Systems, Inc. | Ontario |
| S M E Computer | British Columbia |
| S O S Satellite, Inc. | Quebec |
| S-Frame Software | British Columbia |
| S-P International, Inc. | British Columbia |
| S.A. McNeil and Associates, Inc. | Ontario |
| S.G. Bennett Marketing Services | |
| S.I. Carrière | Quebec |
| S.i. Systems | Alberta |
| S.I. Unik, Inc. | Quebec |
| S.I.C. Biometrics, Inc. | Quebec |
| S.I.R.C. | Quebec |
| S.L.P. Informatique | Quebec |
| S.M. Internet Solutions, Inc. | Ontario |
| S.O.S. Informatique | Quebec |
| S2B Solution | Quebec |
| s2h, Inc. | Ontario |
| S2K Technologies, Inc. | Quebec |
| S3 Technologies | Quebec |
| SA Media | |
| SA+CO | Quebec |
| SAAS North | British Columbia |
| SaaSberry Labs | |
| SaaSnic Technologies | |
| SaaSpasse | |
| Saaspect | |
| SaaSquatch | |
| SaaSTech Servers | Saskatchewan |
| SaasyCloud | |
| SABA Imaging Solutions, Inc. | Ontario |
| Sabeta IP | |
| Sabourin Web & Media | |
| Sabre Communications | |
| Sabre Software & Consulting Ltd | Alberta |
| SabrTech | |
| Sabytel Technologies, Inc. | Ontario |
| SADC de la région de Coaticook | |
| SADC des Sources | |
| Safe and Secure Computing Canada | Ontario |