| Sevocity | |
| SevOne, Inc. | Massachusetts |
| Sew Good Software, Inc. | Florida |
| SEW, Inc. | California |
| Sewanee The University of the South | Tennessee |
| Seward Capital | North Carolina |
| Sewel Industrial Electronics, Inc. | Kentucky |
| Sewell Development Corporation | Utah |
| Seychelle Media | |
| SEYLTX | |
| SF AppWorks | |
| SF Cable, Inc. | California |
| SF Hacks | California |
| SFA Marketing | |
| SFA Therapeutics, Inc. | |
| sfApex, LLC | Texas |
| SFC Fluidics, Inc. | Arkansas |
| SFCD | California |
| SFCD | New York |
| SFO Bay Area Web Design | |
| SFOX, Inc. | California |
| SFP | Indiana |
| SFPlus Transceiver | Florida |
| SFS Chemical Safety | California |
| SFWP Experts | |
| SG360 | Illinois |
| SGK Media | |
| SGM Design | California |
| SGP Systems | West Virginia |
| SGS Consulting | New Jersey |
| SGS Technologie | Florida |
| SGV Sarc | Virginia |
| SH Technology Consulting | New Jersey |
| SH Web Commerce, Inc. | Washington |
| SH3 Computer Systems, Inc. | Virginia |
| Shadaux | Florida |
| Shadbox Infosystem, LLC | Wyoming |
| ShadeCraft | California |
| Shades of Media | |
| ShadeTree Software | Pennsylvania |
| Shadin Company, Inc. | Minnesota |
| Shadow Digital | |
| Shadow Ventures | |
| Shadowbox Web Design | South Carolina |
| ShadowDezign | California |
| ShadowDragon, LLC | Wyoming |
| Shadowserver Foundation | New Jersey |
| Shaeba Corporation | |
| Shah Software | Texas |
| Shailen Lodhia | New Jersey |