| Shirer Burkett | |
| Shiru, Inc. | California |
| Shively Labs | California |
| Shkalix | |
| Shmoop University, Inc. | |
| Shoals Business Incubator | |
| Shockform Aeronautics, Inc. | |
| Shocking Internet Services | California |
| Shockoe.com, LLC | Virginia |
| Shockwave Medical | California |
| Shockwave Solutions | Minnesota |
| Shodan | Texas |
| ShoeFitts Marketing | Oregon |
| Shoelace, Inc. | |
| Shogun | California |
| Shokworks, Inc. | |
| Shompton | |
| Shootfish | |
| Shop Boss | |
| Shop Data Systems | Texas |
| Shop Floor Automation | California |
| Shop for bandwidth | Nevada |
| Shop Texas Electricity | |
| Shop-Ware, Inc. | California |
| ShopAdvisor, Inc. | Massachusetts |
| ShopCAM | Michigan |
| ShopCity.com | Delaware |
| ShopController | Arizona |
| Shopdev | California |
| Shopgenie | |
| ShopHero, Inc. | Utah |
| Shopibro | |
| Shopio Ecommerce Software Solution, Inc. | California |
| Shopision, Inc. | |
| Shopkick, Inc. | |
| Shoplins | |
| Shopmetrics 2015, Inc. | Ohio |
| Shopmonkey, Inc. | |
| ShopNames.com | Wyoming |
| Shoppable | |
| ShopPad | California |
| Shopper Approved | Utah |
| Shoppi Ventures | New York |
| Shopping Cart Elite | New York |
| SHOPpro | Nevada |
| ShopSite, Inc. | Utah |
| ShopSnap | Texas |
| ShopTab | Arizona |
| Shoptech | Connecticut |
| ShopTrade | |