| U.S. Computer Corporation | Louisiana |
| U.S. Consumer Net, Inc. | Tennessee |
| U.S. Converters, LLC | Texas |
| U.S. Department of Energy Joint Genome Institute | |
| U.S. Electrodynamics, Inc. | |
| U.S. Electronics, Inc. | Missouri |
| U.S. Fintech Symposium | Illinois |
| U.S. Games Systems, Inc. | Connecticut |
| U.S. Law Group | |
| U.S. NEXT | Mississippi |
| U.S. Patent and Trademark Office | |
| U.S. Resources, Inc. | Virginia |
| U.S. Robotics Corporation | Illinois |
| U.S. Small Business Administration | District of Columbia |
| U.S. Stem Cell, Inc. | Florida |
| U.S. Toyo Fan | California |
| U.S. Venture Partners | California |
| U.S. Venture, Inc. | Wisconsin |
| U.S.-Ukraine Business Council | |
| u.ventures | Illinois |
| U1 Gaming | Montana |
| U2logic, Inc. | Colorado |
| UA Multimedia, Inc. | California |
| Ualett | Delaware |
| UAPP | |
| UareYou, Inc. | |
| UART.agency | Texas |
| UAV Coach | Tennessee |
| UAV Systems International | Nevada |
| UAVenture Capital Fund, LLC | Arizona |
| UB-04 Software, Inc. | Virginia |
| UBC Payment Solutions, Inc. | New Jersey |
| Uber Clone App | |
| Uber Technologies, Inc. | California |
| Uberall, LLC | Florida |
| UberCloud | California |
| UberConference | California |
| UberData Networks | Ohio |
| Uberduck, Inc. | |
| UberEther, Inc. | |
| Ubergizmo | California |
| Ubertesters, Inc. | New Jersey |
| Ubica | |
| Ubilite, Inc. | |
| Ubimo Ltd | New York |
| Ubiq Security, Inc. | California |
| Ubiqd | New Mexico |
| Ubiquia, Inc. | Arizona |
| Ubiquify Digital Services | |
| Ubiquiti, Inc. | California |