| XYverify Corporation | New York |
| XYZ | Nevada |
| XYZ Advantage | Colorado |
| XYZ Automation, Inc. | Alabama |
| XYZ Venture Capital | |
| Xyzagen | North Carolina |
| XZ Backup | Florida |
| Xzibition Data Communications | Minnesota |
| Xzito Creative Solutions, LLC | Rhode Island |
| Y & M Computer Solutions | California |
| Y Combinator | California |
| Y Media Labs | California |
| Y Scouts | Arizona |
| Y-Designs, Inc. | |
| y-mAbs Therapeutics, Inc. | New Jersey |
| Y-Trap, Inc. | California |
| Y2 Consultants, LLC | Wyoming |
| Y2Payments | Arizona |
| Yaara, Inc. | Delaware |
| Yaara, Inc. | |
| Yabdab, Inc. | Georgia |
| Yabla, Inc. | New York |
| Yacht Controller, LLC | Florida |
| Yadtel | North Carolina |
| Yadu Digital, Inc. | Indiana |
| Yae Labs, Inc. | |
| Yaesu USA | California |
| Yaffe Group | |
| Yagna iQ | Texas |
| Yahara Software | Wisconsin |
| Yahoo | California |
| Yahoo Developer Network | California |
| Yahoo! Research | California |
| Yahoo, Inc. | |
| Yahya Technologies, LLC | Maryland |
| Yai Brands, LLC | Wyoming |
| Yakabod | Maryland |
| Yakima Branding | |
| Yakima Valley College | Washington |
| Yakindo Web Designs, Inc. | Washington |
| Yakoa, Inc. | |
| Yakshna Solutions, Inc. | Virginia |
| Yaldi Marketing | |
| Yale Medicine | Connecticut |
| Yale Quantum Institute | Connecticut |
| Yale Street Creative | Texas |
| Yale University Biomedical Informatics & Data Science | Connecticut |
| Yale University Department of Computer Science | Connecticut |
| Yale University Department of Statistics and Data Science | Connecticut |
| Yale University Mathematics Department | Connecticut |