| Slickfish | Western Australia |
| Slingshot Accelerator Pty Ltd | New South Wales |
| Slinky | |
| Slinky Creative | Western Australia |
| Slinky Interactive Media | |
| Slinky Web Design | Western Australia |
| Slinky Web Hosting | Western Australia |
| Slyp Pty Ltd | New South Wales |
| Small Business Web Designs | New South Wales |
| Small Multiples Pty Ltd | |
| Smart Artist Internet Pty Ltd | New South Wales |
| Smart Foods Consulting Pty Ltd | New South Wales |
| Smart SEO | |
| Smart Token Labs | New South Wales |
| Smart Traffic Pty Ltd | New South Wales |
| Smart Voice | Victoria |
| SmartAsset | Victoria |
| SmartCompany | Victoria |
| SmarterSoft | New South Wales |
| SmartHome Enterprises Pty Ltd | Victoria |
| SmartMove | South Australia |
| Smartnet Pty Ltd | New South Wales |
| SmartrMail Pty Ltd | Victoria |
| SmartRoster | Western Australia |
| SmartUp | Australian Capital Territory |
| Smartware Corporation Pty Ltd | Queensland |
| Smartways Logistics Holdings Pty Ltd | |
| SmartWin Technology Pty Ltd | Victoria |
| Smartwriter.ai | New South Wales |
| Smash Delta | New South Wales |
| SME Solutions | Victoria |
| Smile I.T. | Queensland |
| Smile Marketing | Western Australia |
| Smithsoft Pty Ltd | Queensland |
| SMS Broadcast | Victoria |
| SMSGlobal Holdings Pty Ltd | Victoria |
| Snaptec Australia Pty Ltd | New South Wales |
| Snare Solutions | South Australia |
| Snobal Pty Ltd | Victoria |
| Snowtech Services | Victoria |
| Soar Earth Ltd | Western Australia |
| Soar360 | Victoria |
| Social Connection | Victoria |
| Social Fox Pty Ltd | |
| Social Innovation Summit | Victoria |
| Social Media Status Pty Ltd | |
| Social Meteor | Western Australia |
| SocietyOne Australia Pty Ltd | New South Wales |
| SocietyOne Australia Pty Ltd | |
| Socket Software | Queensland |