| Soda Digital | New South Wales |
| Soft As It Gets Pty Ltd | Victoria |
| Softection Pty Ltd | New South Wales |
| Softel Systems Pty Ltd | Victoria |
| SoftGen Australia | New South Wales |
| Softlog Systems Australia | Western Australia |
| SoftOz | Victoria |
| Softscape Solutions Pty Ltd | Australian Capital Territory |
| Software Development Pty Ltd | Queensland |
| Software Education | Queensland |
| Software Improvements Pty Ltd | Australian Capital Territory |
| Software Mechanics Pty Ltd | Queensland |
| Software Projects Pty Ltd | Queensland |
| Software Publications | New South Wales |
| Software Shortlist Pty Ltd | New South Wales |
| Sol1 | New South Wales |
| Solar eCRM | Victoria |
| SolarCloud | New South Wales |
| Solentive | New South Wales |
| Solid Software Pty Ltd | Victoria |
| Solutions Outsourced | New South Wales |
| Sombrilla Creative | New South Wales |
| Somersoft | Queensland |
| Sometrix Pty Ltd | New South Wales |
| Sonder | Queensland |
| Sonic Clinical Trials | New South Wales |
| Sonic Promotions Pty Ltd | New South Wales |
| Sontech | Western Australia |
| Soprano Design Ltd | New South Wales |
| Sorento Systems Pty Ltd | Victoria |
| SOS Office Equipment | Western Australia |
| SOS Technology Group Pty Ltd | New South Wales |
| Soter Analytics | Western Australia |
| South Australian Apple Users’ Club | South Australia |
| South Australian Institute of Business and Technology | |
| South Australian Space Industry Centre | South Australia |
| Southern Angels | South Australia |
| Southern Cross Payments Ltd | Victoria |
| Southern Cross University | New South Wales |
| Southern Highlands Computer Users Group | New South Wales |
| Southern Star Research Pty Ltd | New South Wales |
| Southmore Capital Pty Ltd | South Australia |
| Space & Co. | Victoria |
| Space Digital | Queensland |
| Space Hi-Fi Pty Ltd | New South Wales |
| Space SA | South Australia |
| Spacely | Victoria |
| Spaceman | New South Wales |
| Spaceship Capital Ltd | New South Wales |
| SPARK Deakin | Victoria |